Version 5.4
Homo sapiens Protein: DTD2
Summary
InnateDB Protein IDBP-91709.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DTD2
Protein Name chromosome 14 open reading frame 126
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000348503
InnateDB Gene IDBG-4405 (DTD2)
Protein Structure
UniProt Annotation
Function Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential). {ECO:0000305}.
Subcellular Localization Cytoplasm {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0008150 biological_process
GO:0019478 D-amino acid catabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR003732 D-tyrosyl-tRNA(Tyr) deacylase
IPR023509 D-Tyr tRNAtyr deacylase-like domain
PFAM PF02580
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96FN9
PhosphoSite PhosphoSite-Q96FN9
TrEMBL
UniProt Splice Variant
Entrez Gene 112487
UniGene Hs.116014
RefSeq
HUGO HGNC:20277
OMIM
CCDS CCDS9643
HPRD 16599
IMGT
EMBL AL139353 AL163973 BC010618 CH471078
GenPept AAH10618 EAW65944 EAW65945

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca