Version 5.4
Homo sapiens Protein: OLFM1
Summary
InnateDB Protein IDBP-91878.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OLFM1
Protein Name olfactomedin 1
Synonyms AMY; NOE1; NOELIN1; OlfA;
Species Homo sapiens
Ensembl Protein ENSP00000360858
InnateDB Gene IDBG-91864 (OLFM1)
Protein Structure
UniProt Annotation
Function May play an important role in regulating the production of neural crest cells by the neural tube. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}. Cell junction, synapse {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001540 beta-amyloid binding
GO:0005515 protein binding
Biological Process
GO:0007399 nervous system development
GO:0051259 protein oligomerization
GO:1902003 regulation of beta-amyloid formation
GO:1902430 negative regulation of beta-amyloid formation
GO:2001223 negative regulation of neuron migration
Cellular Component
GO:0005615 extracellular space
GO:0030054 cell junction
GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro IPR003112 Olfactomedin-like
IPR011047 Quinonprotein alcohol dehydrogenase-like superfamily
IPR022082 Neurogenesis glycoprotein
PFAM PF02191
PF12308
PRINTS
PIRSF
SMART SM00284
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99784
PhosphoSite PhosphoSite-Q99784
TrEMBL Q96BL8
UniProt Splice Variant
Entrez Gene 10439
UniGene Hs.522484
RefSeq NP_001269540
HUGO HGNC:17187
OMIM 605366
CCDS CCDS65184
HPRD 09249
IMGT
EMBL AF035301 AK090818 AK290478 AL159992 AL390778 BC008763 BC011741 BC015437 BK001427 BT007146 D82343 U79299
GenPept AAB50225 AAB88184 AAH08763 AAH11741 AAH15437 AAP35810 BAA11554 BAF83167 BAG52234 DAA01547

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca