InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MTCP1

Summary

InnateDB Protein

IDBP-92326.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MTCP1

Protein Name

mature T-cell proliferation 1

Synonyms

P13MTCP1; p8MTCP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000355058

InnateDB Gene

IDBG-231611 (MTCP1)

Protein Structure

UniProt Annotation

Function

Enhances the phosphorylation and activation of AKT1 and AKT2. {ECO:0000269PubMed:10983986}.

Subcellular Localization

Disease Associations

Note=Detected in T-cell leukemia bearing a t(X;14) translocation. Plays a key role in T-cell prolymphocytic leukemia.

Tissue Specificity

Not found at a significant level in any tissue.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0008283

cell proliferation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR004832 TCL1/MTCP1

PFAM

PF01840

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P56278

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

4515

UniGene

Hs.6917

RefSeq

HUGO

HGNC:7423

OMIM

300116

CCDS

CCDS44027

HPRD

02122

IMGT

EMBL

BX470111 CH471172 Z24459

GenPept

CAA80828 CAI41656 EAW72642