Version 5.4
Homo sapiens Protein: SH3BGRL2
Summary
InnateDB Protein IDBP-93487.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH3BGRL2
Protein Name SH3 domain binding glutamic acid-rich protein like 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000358853
InnateDB Gene IDBG-93485 (SH3BGRL2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000269PubMed:12095696}.
Disease Associations
Tissue Specificity Highly expressed in brain, placenta, liver and kidney. Expressed in retina. {ECO:0000269PubMed:12095696}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0009055 electron carrier activity
GO:0015035 protein disulfide oxidoreductase activity
GO:0017124 SH3 domain binding
Biological Process
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005634 nucleus
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002109 Glutaredoxin
IPR006993 SH3-binding, glutamic acid-rich protein
IPR012336 Thioredoxin-like fold
PFAM PF00462
PF04908
PF13098
PF13192
PF13462
PF13905
PRINTS
PIRSF PIRSF008142
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UJC5
PhosphoSite PhosphoSite-Q9UJC5
TrEMBL
UniProt Splice Variant
Entrez Gene 83699
UniGene Hs.743659
RefSeq NP_113657
HUGO HGNC:15567
OMIM 615678
CCDS CCDS4991
HPRD 15331
IMGT
EMBL AF340151 AJ297972 AK311757 AL035700 AL451064 BC040489 BC052987 BC060799 BC070059 BC109043 BC109044 CH471051
GenPept AAH40489 AAH52987 AAH60799 AAH70059 AAI09044 AAI09045 AAK37526 BAG34700 CAB55867 CAC35771 CAH70932 EAW48703

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca