Version 5.4
Homo sapiens Protein: TUBGCP2
Summary
InnateDB Protein IDBP-93659.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBGCP2
Protein Name tubulin, gamma complex associated protein 2
Synonyms GCP-2; GCP2; Grip103; h103p; hGCP2; hSpc97; SPBC97; Spc97p;
Species Homo sapiens
Ensembl Protein ENSP00000357551
InnateDB Gene IDBG-93655 (TUBGCP2)
Protein Structure
UniProt Annotation
Function Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Disease Associations
Tissue Specificity Ubiquitously expressed.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 71 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 71 [view]
Protein-Protein 71 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0006461 protein complex assembly
GO:0007020 microtubule nucleation
Cellular Component
GO:0000922 spindle pole
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005881 cytoplasmic microtubule
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR007259 Gamma-tubulin complex component protein
IPR014798 DNA mimic Ocr
PFAM PF04130
PF08684
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BSJ2
PhosphoSite PhosphoSite-Q9BSJ2
TrEMBL B3KTU7
UniProt Splice Variant
Entrez Gene 10844
UniGene Hs.523370
RefSeq NP_006650
HUGO HGNC:18599
OMIM
CCDS CCDS7676
HPRD 18245
IMGT
EMBL AF042379 AK096087 AK297251 AL360181 AL592071 BC005011 BC093770 BC111957 BC143247
GenPept AAC39728 AAH93770 AAI11958 AAI43248 BAG53209 BAG59730 CAH70275

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca