Version 5.4
Homo sapiens Protein: GPR63
Summary
InnateDB Protein IDBP-94471.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR63
Protein Name G protein-coupled receptor 63
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000229955
InnateDB Gene IDBG-94469 (GPR63)
Protein Structure
UniProt Annotation
Function Orphan receptor. May play a role in brain function.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Expressed in brain; detected in the frontal cortex, with lower levels in the thalamus, caudate, hypothalamus and midbrain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0008150 biological_process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
PFAM PF00001
PF10320
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BZJ6
PhosphoSite PhosphoSite-Q9BZJ6
TrEMBL A8K1C4
UniProt Splice Variant
Entrez Gene 81491
UniGene Hs.221364
RefSeq NP_110411
HUGO HGNC:13302
OMIM 606915
CCDS CCDS5036
HPRD 06076
IMGT
EMBL AB030566 AF317654 AK289839 AK313535 AL033379 BC067465 BC067469 CH471051 FJ348260
GenPept AAH67465 AAH67469 AAK12639 ACI96304 BAB20031 BAF82528 BAG36312 CAB55871 EAW48502

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca