Version 5.4
Homo sapiens Protein: SCML4
Summary
InnateDB Protein IDBP-94961.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCML4
Protein Name sex comb on midleg-like 4 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000358018
InnateDB Gene IDBG-94957 (SCML4)
Protein Structure
UniProt Annotation
Function Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001660 Sterile alpha motif domain
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1
IPR021987 Protein of unknown function DUF3588
PFAM PF00536
PF12140
PRINTS
PIRSF
SMART SM00454
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N228
PhosphoSite PhosphoSite-Q8N228
TrEMBL
UniProt Splice Variant
Entrez Gene 256380
UniGene Hs.629466
RefSeq NP_001273337
HUGO HGNC:21397
OMIM
CCDS CCDS69163
HPRD 10212
IMGT
EMBL AK093571 AL096816 AL512592 BC033286 CH471051
GenPept AAH33286 BAC04198 CAI13632 CAI42848 CAQ08122 CAQ08123 CAX12112 EAW48394 EAW48395

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca