InnateDB Protein
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IDBP-95282.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GMEB1
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Protein Name
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glucocorticoid modulatory element binding protein 1
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Synonyms
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P96PIF; PIF96;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000362922
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InnateDB Gene
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IDBG-95280 (GMEB1)
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Protein Structure
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Function |
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
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Subcellular Localization |
Nucleus. Cytoplasm. Note=May be also cytoplasmic.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
17
[view]
|
Protein-Protein |
17
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000770
SAND domain
IPR010919
SAND domain-like
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PFAM |
PF01342
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PRINTS |
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PIRSF |
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SMART |
SM00258
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y692
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PhosphoSite |
PhosphoSite-Q9Y692
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TrEMBL |
B1AT47
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UniProt Splice Variant |
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Entrez Gene |
10691
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UniGene |
Hs.713771
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RefSeq |
NP_077808
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HUGO |
HGNC:4370
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OMIM |
604409
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CCDS |
CCDS328
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HPRD |
16059
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IMGT |
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EMBL |
AF099013
AF173868
AF203694
AK000892
AK315436
AL645729
BC001473
CH471059
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GenPept |
AAD39355
AAD51352
AAG01189
AAH01473
BAA91410
BAG37824
CAH72427
EAX07676
EAX07677
EAX07678
EAX07679
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