InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GTF3C6

Summary

InnateDB Protein

IDBP-95323.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GTF3C6

Protein Name

general transcription factor IIIC, polypeptide 6, alpha 35kDa

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000357863

InnateDB Gene

IDBG-95321 (GTF3C6)

Protein Structure

UniProt Annotation

Function

Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. {ECO:0000269PubMed:17409385}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:17409385}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006383	transcription from RNA polymerase III promoter
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter
GO:0042797	tRNA transcription from RNA polymerase III promoter