Version 5.4
Homo sapiens Protein: WDR76
Summary
InnateDB Protein IDBP-9574.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR76
Protein Name WD repeat domain 76
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000263795
InnateDB Gene IDBG-9570 (WDR76)
Protein Structure
UniProt Annotation
Function Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H967
PhosphoSite PhosphoSite-Q9H967
TrEMBL C9JE56
UniProt Splice Variant
Entrez Gene 79968
UniGene Hs.250154
RefSeq NP_079184
HUGO HGNC:25773
OMIM
CCDS CCDS10106
HPRD 07804
IMGT
EMBL AC018512 AC023356 AK023035 AK290933 BC025247 BC051855 EF011624
GenPept AAH25247 AAH51855 ABK41114 BAB14369 BAF83622

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca