InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TRMT11

Summary

InnateDB Protein

IDBP-96157.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRMT11

Protein Name

tRNA methyltransferase 11 homolog (S. cerevisiae)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000357316

InnateDB Gene

IDBG-96151 (TRMT11)

Protein Structure

UniProt Annotation

Function

Catalytic subunit of an S-adenosyl-L-methionine- dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000049	tRNA binding
GO:0008168	methyltransferase activity

Biological Process

GO:0008033	tRNA processing
GO:0032259	methylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000241 Putative RNA methylase domain
IPR002296 N6 adenine-specific DNA methyltransferase, N12 class
IPR016691 tRNA guanosine-2\'-O-methyltransferase, TRM11
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01170

PRINTS

PR00507

PIRSF

PIRSF017259

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt