Homo sapiens Protein: PODN | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-98696.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | PODN | ||||||
Protein Name | podocan | ||||||
Synonyms | |||||||
Species | Homo sapiens | ||||||
Ensembl Protein | ENSP00000308315 | ||||||
InnateDB Gene | IDBG-98692 (PODN) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | Negatively regulates cell proliferation and cell migration. {ECO:0000269PubMed:15063725}. | ||||||
Subcellular Localization | Isoform 1: Secreted, extracellular space, extracellular matrix.Isoform 2: Cytoplasm {ECO:0000305}.Isoform 3: Cytoplasm {ECO:0000305}.Isoform 4: Cytoplasm {ECO:0000305}. | ||||||
Disease Associations | |||||||
Tissue Specificity | Kidney, heart, liver, pancreas and vascular smooth muscle cells. Also detected in aortic intima (at protein level). {ECO:0000269PubMed:12796502, ECO:0000269PubMed:15063725, ECO:0000269PubMed:20551380}. | ||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | |||||||
InterPro |
IPR000372
Leucine-rich repeat-containing N-terminal IPR001611 Leucine-rich repeat IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype IPR003591 Leucine-rich repeat, typical subtype |
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PFAM |
PF01462
PF00560 PF13504 PF13855 |
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PRINTS | |||||||
PIRSF | |||||||
SMART |
SM00013
SM00368 SM00369 |
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TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | Q7Z5L7 | ||||||
PhosphoSite | PhosphoSite-Q7Z5L7 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 127435 | ||||||
UniGene | Hs.743706 | ||||||
RefSeq | NP_714914 | ||||||
HUGO | HGNC:23174 | ||||||
OMIM | 608661 | ||||||
CCDS | CCDS573 | ||||||
HPRD | 10557 | ||||||
IMGT | |||||||
EMBL | AK296649 AK299375 AK304599 AL445183 AY313607 AY358294 BC028292 BC030608 | ||||||
GenPept | AAH28292 AAH30608 AAP79898 AAQ88661 BAG59247 BAG61365 BAG65385 CAH72591 CAH72592 | ||||||