Homo sapiens Protein: T
Summary
InnateDB Protein IDBP-98926.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol T
Protein Name T, brachyury homolog (mouse)
Synonyms SAVA; TFT;
Species Homo sapiens
Ensembl Protein ENSP00000355836
InnateDB Gene IDBG-98920 (T)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0001191 RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0003007 heart morphogenesis
GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0007498 mesoderm development
GO:0008595 anterior/posterior axis specification, embryo
GO:0090009 primitive streak formation
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001699 Transcription factor, T-box
IPR002070 Transcription factor, Brachyury
IPR008967 p53-like transcription factor, DNA-binding
PFAM PF00907
PRINTS PR00937
PR00938
PIRSF
SMART SM00425
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O15178
PhosphoSite PhosphoSite-O15178
TrEMBL H0YM91
UniProt Splice Variant
Entrez Gene 6862
UniGene Hs.389457
RefSeq NP_001257413
HUGO HGNC:11515
OMIM 601397
CCDS CCDS59045
HPRD 03236
IMGT
EMBL AJ001699 AL627443 BC098425
GenPept AAH98425 CAA04938 CAI14269