Version 5.4
| Homo sapiens Protein: INSL5 | |||||
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| Summary | |||||
| InnateDB Protein | IDBP-99515.6 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | INSL5 | ||||
| Protein Name | insulin-like 5 | ||||
| Synonyms | PRO182; UNQ156; | ||||
| Species | Homo sapiens | ||||
| Ensembl Protein | ENSP00000302724 | ||||
| InnateDB Gene | IDBG-99513 (INSL5) | ||||
| Protein Structure |
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| UniProt Annotation | |||||
| Function | May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor. | ||||
| Subcellular Localization | Secreted. | ||||
| Disease Associations | |||||
| Tissue Specificity | Highly expressed in rectum with lower levels in uterus and ascending and descending colon. {ECO:0000269PubMed:10458910}. | ||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||
| PDB ID | |||||
| InterPro |
IPR016179
Insulin-like |
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| PFAM |
PF00049
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| PRINTS | |||||
| PIRSF | |||||
| SMART |
SM00078
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| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | Q9Y5Q6 | ||||
| PhosphoSite | PhosphoSite- | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 10022 | ||||
| UniGene | Hs.251380 | ||||
| RefSeq | NP_005469 | ||||
| HUGO | HGNC:6088 | ||||
| OMIM | 606413 | ||||
| CCDS | CCDS634 | ||||
| HPRD | 08400 | ||||
| IMGT | |||||
| EMBL | AF133816 AL354978 AY359030 BC101646 BC101648 | ||||
| GenPept | AAD29686 AAI01647 AAI01649 AAQ89389 CAH71844 | ||||