Version 5.4
Homo sapiens Protein: DNAJB4
Summary
InnateDB Protein IDBP-99861.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAJB4
Protein Name DnaJ (Hsp40) homolog, subfamily B, member 4
Synonyms DjB4; DNAJW; HLJ1;
Species Homo sapiens
Ensembl Protein ENSP00000359799
InnateDB Gene IDBG-99859 (DNAJB4)
Protein Structure
UniProt Annotation
Function Probable chaperone.
Subcellular Localization Cytoplasm. Cell membrane. Note=Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.
Disease Associations
Tissue Specificity Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver. {ECO:0000269PubMed:9546042}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 20 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051082 unfolded protein binding
GO:0051087 chaperone binding
Biological Process
GO:0006457 protein folding
GO:0006986 response to unfolded protein
GO:0009408 response to heat
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001623 DnaJ domain
IPR002939 Chaperone DnaJ, C-terminal
IPR008971 HSP40/DnaJ peptide-binding
PFAM PF00226
PF01556
PRINTS PR00625
PIRSF
SMART SM00271
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UDY4
PhosphoSite PhosphoSite-Q9UDY4
TrEMBL C9JUL4
UniProt Splice Variant
Entrez Gene 11080
UniGene Hs.689996
RefSeq NP_008965
HUGO HGNC:14886
OMIM 611327
CCDS CCDS684
HPRD 07486
IMGT
EMBL AC096948 AC103591 AK297985 AK313205 BC034721 CH471059 U40992 U41290
GenPept AAB07346 AAC14483 AAH34721 BAG36021 BAG60294 EAX06354 EAX06355

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca