Homo sapiens Gene: CLCA4
Summary
InnateDB Gene IDBG-100084.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLCA4
Gene Name chloride channel accessory 4
Synonyms CaCC; CaCC2;
Species Homo sapiens
Ensembl Gene ENSG00000016602
Encoded Proteins
chloride channel accessory 4
Protein Structure
Entrez Gene
Summary The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Alternative splicing results in multiple transcript variants, only one of which is thought to be protein coding. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:86547078-86580754
Strand Forward strand
Band p22.3
Transcripts
ENST00000370563 ENSP00000359594
ENST00000496322
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005254 chloride channel activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006821 chloride transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Stimuli-sensing channels pathway
Orphan transporters pathway
Ion channel transport pathway
KEGG
Olfactory transduction pathway
Pancreatic secretion pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q14CN2
TrEMBL Q9NXP1
UniProt Splice Variant
Entrez Gene 22802
UniGene Hs.567422 Hs.607191
RefSeq NM_012128 XM_006710453
HUGO HGNC:2018
OMIM
CCDS CCDS41355
HPRD 16719
IMGT
EMBL AF127035 AK000138 AL122002 AY358470 BC113687 BC113689
GenPept AAD48398 AAI13688 AAI13690 AAQ88834 BAA90969 CAI22170
ImmGen CLCA4 (murine)
RNA Seq Atlas 22802