Homo sapiens Gene: GBP4
Summary
InnateDB Gene IDBG-100177.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GBP4
Gene Name guanylate binding protein 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000162654
Encoded Proteins
guanylate binding protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:89181148-89198932
Strand Reverse strand
Band p22.2
Transcripts
ENST00000355754 ENSP00000359490
ENST00000471938
ENST00000481397
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Interferon gamma signaling pathway
Cytokine Signaling in Immune system pathway
Interferon Signaling pathway
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q96PP9
TrEMBL B4E2F1
UniProt Splice Variant
Entrez Gene 115361
UniGene Hs.409925
RefSeq NM_052941
HUGO HGNC:20480
OMIM 612466
CCDS CCDS721
HPRD
IMGT
EMBL AF288814 AK131094 AK304245 AK312417 AL832576 BC017889 BC070055
GenPept AAH17889 AAH70055 AAL02054 BAC85144 BAG35327 BAG65113 CAD89936
RNA Seq Atlas 115361