Version 5.4
Homo sapiens Gene: DNTTIP2
Summary
InnateDB Gene IDBG-100352.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNTTIP2
Gene Name deoxynucleotidyltransferase, terminal, interacting protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000067334
Encoded Proteins
IDBP-100354
deoxynucleotidyltransferase, terminal, interacting protein 2
IDBP-386878
deoxynucleotidyltransferase, terminal, interacting protein 2
IDBP-585733
deoxynucleotidyltransferase, terminal, interacting protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:93866283-93879918
Strand Reverse strand
Band p22.1
Transcripts
ENST00000359208 ENSP00000352137
ENST00000436063 ENSP00000411010
ENST00000496535
ENST00000462746
ENST00000460191
ENST00000496672
ENST00000528680 ENSP00000434261
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039756
View Gene Order
ENSBTAG00000047679
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.601998 Hs.85769
RefSeq NM_014597
HUGO
OMIM
CCDS CCDS44174
HPRD 09994
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca