Version 5.4
Homo sapiens Gene: RBM15
Summary
InnateDB Gene IDBG-100966.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBM15
Gene Name RNA binding motif protein 15
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000162775
Encoded Proteins
IDBP-100968
RNA binding motif protein 15
IDBP-812278
RNA binding motif protein 15
IDBP-812274
RNA binding motif protein 15
IDBP-812279
RNA binding motif protein 15
IDBP-812280
RNA binding motif protein 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:110338506-110346681
Strand Forward strand
Band p13.3
Transcripts
ENST00000369784 ENSP00000358799
ENST00000487146 ENSP00000473552
ENST00000602849 ENSP00000473638
ENST00000617047 ENSP00000480399
ENST00000618772 ENSP00000483133
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 23 [view]
Protein-DNA 4 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001569 patterning of blood vessels
GO:0007221 positive regulation of transcription of Notch receptor target
GO:0016032 viral process
GO:0045638 negative regulation of myeloid cell differentiation
GO:0048536 spleen development
GO:0060412 ventricular septum morphogenesis
GO:0060674 placenta blood vessel development
Cellular Component
GO:0005634 nucleus
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048109
View Gene Order
ENSBTAG00000012555
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001201545 NM_022768
HUGO
OMIM
CCDS CCDS59198 CCDS822
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca