Version 5.4
Homo sapiens Gene: CHI3L2
Summary
InnateDB Gene IDBG-101027.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHI3L2
Gene Name chitinase 3-like 2
Synonyms CHIL2; YKL-39; YKL39
Species Homo sapiens
Ensembl Gene ENSG00000064886
Encoded Proteins
IDBP-101029
chitinase 3-like 2
IDBP-101031
chitinase 3-like 2
IDBP-596896
chitinase 3-like 2
IDBP-593354
chitinase 3-like 2
IDBP-585415
chitinase 3-like 2
IDBP-584945
chitinase 3-like 2
IDBP-588816
chitinase 3-like 2
IDBP-596619
chitinase 3-like 2
IDBP-585378
chitinase 3-like 2
IDBP-585184
chitinase 3-like 2
IDBP-603223
chitinase 3-like 2
IDBP-600859
chitinase 3-like 2
IDBP-596413
chitinase 3-like 2
IDBP-583507
chitinase 3-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:111200771-111243440
Strand Forward strand
Band p13.2
Transcripts
ENST00000369748 ENSP00000358763
ENST00000369744 ENSP00000358759
ENST00000445067 ENSP00000437082
ENST00000486561 ENSP00000431968
ENST00000474304 ENSP00000436380
ENST00000466741 ENSP00000437086
ENST00000477185 ENSP00000436272
ENST00000467038 ENSP00000431978
ENST00000497587 ENSP00000436006
ENST00000497220 ENSP00000435250
ENST00000472825 ENSP00000435935
ENST00000528451 ENSP00000436077
ENST00000526684
ENST00000530597
ENST00000524472 ENSP00000432049
ENST00000533831 ENSP00000433176
ENST00000529459
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004568 chitinase activity
GO:0008061 chitin binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006032 chitin catabolic process
Cellular Component
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL E9PII8
UniProt Splice Variant
Entrez Gene 1117
UniGene Hs.680176
RefSeq NM_001025197 NM_001025199 NM_004000
HUGO HGNC:1933
OMIM 601526
CCDS CCDS30802 CCDS30803 CCDS41367
HPRD 03315
IMGT
EMBL AL355816 AL513202
GenPept
RNA Seq Atlas 1117

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca