Version 5.4
Homo sapiens Gene: TSPAN2
Summary
InnateDB Gene IDBG-101340.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN2
Gene Name tetraspanin 2
Synonyms NET3; TSN2; TSPAN-2
Species Homo sapiens
Ensembl Gene ENSG00000134198
Encoded Proteins
IDBP-101342
tetraspanin 2
IDBP-101344
tetraspanin 2
IDBP-101346
tetraspanin 2
IDBP-387871
tetraspanin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:115048011-115089500
Strand Reverse strand
Band p13.2
Transcripts
ENST00000369516 ENSP00000358529
ENST00000369515 ENSP00000358528
ENST00000369514 ENSP00000358527
ENST00000433172 ENSP00000415256
ENST00000491992
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006954 inflammatory response
GO:0007420 brain development
GO:0014002 astrocyte development
GO:0014005 microglia development
GO:0042552 myelination
GO:0048709 oligodendrocyte differentiation
GO:0061564 axon development
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0043209 myelin sheath
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027858
View Gene Order
ENSBTAG00000015961
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.310458
RefSeq NM_005725
HUGO
OMIM
CCDS CCDS881
HPRD 18233
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca