Version 5.4
Homo sapiens Gene: NHLH2
Summary
InnateDB Gene IDBG-101364.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NHLH2
Gene Name nescient helix loop helix 2
Synonyms bHLHa34; HEN2; NSCL2
Species Homo sapiens
Ensembl Gene ENSG00000177551
Encoded Proteins
IDBP-101366
nescient helix loop helix 2
IDBP-101368
nescient helix loop helix 2
IDBP-387877
nescient helix loop helix 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:115836377-115843917
Strand Reverse strand
Band p13.1
Transcripts
ENST00000320238 ENSP00000322087
ENST00000369506 ENSP00000358519
ENST00000429731 ENSP00000405062
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007417 central nervous system development
GO:0007617 mating behavior
GO:0030154 cell differentiation
GO:0042698 ovulation cycle
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048540
View Gene Order
ENSBTAG00000015067
Not yet available
Cross-References
SwissProt
TrEMBL A6PVY9
UniProt Splice Variant
Entrez Gene 4808
UniGene Hs.46296 Hs.617784 Hs.707180
RefSeq NM_001111061 NM_005599
HUGO HGNC:7818
OMIM 162361
CCDS CCDS885
HPRD 01213
IMGT
EMBL AL449264
GenPept
RNA Seq Atlas 4808

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca