InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NHLH2

Summary

InnateDB Protein

IDBP-101366.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NHLH2

Protein Name

nescient helix loop helix 2

Synonyms

bHLHa34; HEN2; NSCL2;

Species

Homo sapiens

Ensembl Protein

ENSP00000322087

InnateDB Gene

IDBG-101364 (NHLH2)

Protein Structure

UniProt Annotation

Function

May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001102	RNA polymerase II activating transcription factor binding
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046983	protein dimerization activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0007417	central nervous system development
GO:0030154	cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity