Version 5.4
Homo sapiens Gene: TBX15
Summary
InnateDB Gene IDBG-101478.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBX15
Gene Name T-box 15
Synonyms TBX14
Species Homo sapiens
Ensembl Gene ENSG00000092607
Encoded Proteins
IDBP-101480
T-box 15
IDBP-101482
T-box 15
IDBP-387911
T-box 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:118883046-118989556
Strand Reverse strand
Band p12
Transcripts
ENST00000207157 ENSP00000207157
ENST00000369429 ENSP00000358437
ENST00000449873 ENSP00000398625
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0001106 RNA polymerase II transcription corepressor activity
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048704 embryonic skeletal system morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0070722 Tle3-Aes complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027868
View Gene Order
ENSBTAG00000007767
Not yet available
Cross-References
SwissProt
TrEMBL Q5JT55
UniProt Splice Variant
Entrez Gene 6913
UniGene Hs.146196 Hs.626431
RefSeq XM_005271161 NM_152380 XM_005271162
HUGO HGNC:11594
OMIM 604127
CCDS CCDS30816
HPRD 16035
IMGT
EMBL AL139420 AL357045
GenPept
RNA Seq Atlas 6913

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca