Version 5.4
Homo sapiens Gene: PEX11B
Summary
InnateDB Gene IDBG-101742.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PEX11B
Gene Name peroxisomal biogenesis factor 11 beta
Synonyms PEX11-BETA; PEX14B
Species Homo sapiens
Ensembl Gene ENSG00000131779
Encoded Proteins
IDBP-101744
peroxisomal biogenesis factor 11 beta
IDBP-388083
peroxisomal biogenesis factor 11 beta
IDBP-599451
peroxisomal biogenesis factor 11 beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene facilitates peroxisomal proliferation and interacts with PEX19. The encoded protein is found in the peroxisomal membrane. Several transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:145911350-145918837
Strand Reverse strand
Band q21.1
Transcripts
ENST00000369306 ENSP00000358312
ENST00000428634 ENSP00000414018
ENST00000537888 ENSP00000437510
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 9 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0007031 peroxisome organization
GO:0007165 signal transduction
GO:0016559 peroxisome fission
GO:0044375 regulation of peroxisome size
GO:0051260 protein homooligomerization
Cellular Component
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005779 integral component of peroxisomal membrane
GO:0016020 membrane
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028102
View Gene Order
ENSBTAG00000008372
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt O96011
TrEMBL A0A024R4E7 B3KSS3 H7C3V6
UniProt Splice Variant
Entrez Gene 8799
UniGene Hs.604654 Hs.727252
RefSeq NM_003846 NM_001184795
HUGO HGNC:8853
OMIM 603867
CCDS CCDS72871 CCDS72870
HPRD 04844
IMGT
EMBL AB018080 AF093670 AK023991 AK094173 AK301983 AL160282 BC011963 CH471244 CR542047
GenPept AAC78660 AAH11963 BAA34812 BAG51247 BAG52835 BAG63391 CAG46844 EAW71422 EAW71423
RNA Seq Atlas 8799

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca