Version 5.4
Homo sapiens Gene: SNX10
Summary
InnateDB Gene IDBG-10202.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX10
Gene Name sorting nexin 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000086300
Encoded Proteins
IDBP-10204
sorting nexin 10
IDBP-237638
sorting nexin 10
IDBP-294691
sorting nexin 10
IDBP-294689
sorting nexin 10
IDBP-369023
sorting nexin 10
IDBP-369026
sorting nexin 10
IDBP-369032
sorting nexin 10
IDBP-806327
sorting nexin 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene may play a role in regulating endosome homeostasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:26291895-26374329
Strand Forward strand
Band p15.2
Transcripts
ENST00000338523 ENSP00000343709
ENST00000396376 ENSP00000379661
ENST00000409367 ENSP00000387274
ENST00000409838 ENSP00000386540
ENST00000416246 ENSP00000408164
ENST00000412416 ENSP00000393690
ENST00000446848 ENSP00000395474
ENST00000462993
ENST00000619420 ENSP00000478710
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005545 1-phosphatidylinositol binding
GO:0035091 phosphatidylinositol binding
GO:0051117 ATPase binding
Biological Process
GO:0006886 intracellular protein transport
GO:0007032 endosome organization
GO:0030316 osteoclast differentiation
GO:0042384 cilium assembly
GO:0061512 protein localization to cilium
GO:0071539 protein localization to centrosome
Cellular Component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005813 centrosome
GO:0031313 extrinsic component of endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038301
View Gene Order
ENSBTAG00000001822
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001199835 NM_001199837 NM_001199838 NM_013322 XM_006715710 XM_006715711 XM_006715712
HUGO
OMIM
CCDS CCDS5399 CCDS56470
HPRD 15409
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca