Version 5.4
Homo sapiens Gene: SELENBP1
Summary
InnateDB Gene IDBG-102363.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SELENBP1
Gene Name selenium binding protein 1
Synonyms HEL-S-134P; hSBP; LPSB; SBP56; SP56
Species Homo sapiens
Ensembl Gene ENSG00000143416
Encoded Proteins
IDBP-102365
selenium binding protein 1
IDBP-388542
selenium binding protein 1
IDBP-388544
selenium binding protein 1
IDBP-388545
selenium binding protein 1
IDBP-388546
selenium binding protein 1
IDBP-388547
selenium binding protein 1
IDBP-388548
selenium binding protein 1
IDBP-388549
selenium binding protein 1
IDBP-388550
selenium binding protein 1
IDBP-388551
selenium binding protein 1
IDBP-388553
selenium binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:151364302-151372733
Strand Reverse strand
Band q21.3
Transcripts
ENST00000368868 ENSP00000357861
ENST00000447402 ENSP00000413960
ENST00000443708 ENSP00000402531
ENST00000455397 ENSP00000395637
ENST00000427977 ENSP00000412816
ENST00000423070 ENSP00000416206
ENST00000424475 ENSP00000396209
ENST00000458566 ENSP00000406222
ENST00000426705 ENSP00000397261
ENST00000455839 ENSP00000390433
ENST00000427867 ENSP00000400841
ENST00000493560
ENST00000474352
ENST00000470345
ENST00000463664
ENST00000465273
ENST00000473693
ENST00000492643
ENST00000498494
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated
Total 32 [view]
Protein-Protein 31 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008430 selenium binding
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005829 cytosol
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000068874
View Gene Order
ENSBTAG00000008091
Not yet available
Cross-References
SwissProt
TrEMBL A6PVX1
UniProt Splice Variant
Entrez Gene 8991
UniGene Hs.632460
RefSeq NM_001258288 NM_001258289 NM_003944
HUGO HGNC:10719
OMIM 604188
CCDS CCDS58027 CCDS60266 CCDS995
HPRD 05007
IMGT
EMBL AL391069
GenPept
RNA Seq Atlas 8991

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca