Version 5.4
Homo sapiens Gene: FLG2
Summary
InnateDB Gene IDBG-102488.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FLG2
Gene Name filaggrin family member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143520
Encoded Proteins
IDBP-102476
filaggrin family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:152348735-152360006
Strand Reverse strand
Band q21.3
Transcripts
ENST00000388718 ENSP00000373370
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005509 calcium ion binding
Biological Process
GO:0061436 establishment of skin barrier
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049133
View Gene Order
ENSBTAG00000011756
Not yet available
Cross-References
SwissProt Q5D862
TrEMBL
UniProt Splice Variant
Entrez Gene 388698
UniGene Hs.156124
RefSeq NM_001014342
HUGO HGNC:33276
OMIM
CCDS CCDS30861
HPRD
IMGT
EMBL AL356504 AY827490 DQ118293
GenPept AAX12417 AAZ99029 CAC13173
RNA Seq Atlas 388698

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca