Homo sapiens Gene: CRNN
Summary
InnateDB Gene IDBG-102491.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRNN
Gene Name cornulin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143536
Encoded Proteins
cornulin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:152409243-152414263
Strand Reverse strand
Band q21.3
Transcripts
ENST00000271835 ENSP00000271835
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0009408 response to heat
GO:0016337 single organismal cell-cell adhesion
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q9UBG3
TrEMBL
UniProt Splice Variant
Entrez Gene 49860
UniGene Hs.242057
RefSeq NM_016190 XM_006711346
HUGO HGNC:1230
OMIM 611312
CCDS CCDS1010
HPRD
IMGT
EMBL AF077831 AF185276 AK316568 AL135842 BC030807 CH471121
GenPept AAD55747 AAF00514 AAH30807 BAG38157 CAI23349 EAW53381
RNA Seq Atlas 49860