Homo sapiens Gene: S100A2
Summary
InnateDB Gene IDBG-102707.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100A2
Gene Name S100 calcium binding protein A2
Synonyms CAN19; S100L
Species Homo sapiens
Ensembl Gene ENSG00000196754
Encoded Proteins
S100 calcium binding protein A2
S100 calcium binding protein A2
S100 calcium binding protein A2
S100 calcium binding protein A2
S100 calcium binding protein A2
S100 calcium binding protein A2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:153561108-153567890
Strand Reverse strand
Band q21.3
Transcripts
ENST00000368710 ENSP00000357699
ENST00000368709 ENSP00000357698
ENST00000368708 ENSP00000357697
ENST00000368707 ENSP00000357696
ENST00000487430 ENSP00000473260
ENST00000497140 ENSP00000473489
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0043542 endothelial cell migration
Cellular Component
GO:0005575 cellular_component
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
Direct p53 effectors
p73 transcription factor network
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.618501 Hs.734133
RefSeq NM_005978
HUGO
OMIM
CCDS CCDS1044
HPRD 01508
IMGT
EMBL
GenPept
RNA Seq Atlas