Homo sapiens Protein: S100A2
Summary
InnateDB Protein IDBP-102715.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100A2
Protein Name S100 calcium binding protein A2
Synonyms CAN19; S100L;
Species Homo sapiens
Ensembl Protein ENSP00000357697
InnateDB Gene IDBG-102707 (S100A2)
Protein Structure
UniProt Annotation
Function May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth. {ECO:0000269PubMed:1372446, ECO:0000269PubMed:22399290}.
Subcellular Localization
Disease Associations
Tissue Specificity A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes. {ECO:0000269PubMed:1372446}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0043542 endothelial cell migration
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
PFAM PF00036
PF13202
PF13405
PF01023
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P29034
PhosphoSite PhosphoSite-P29034
TrEMBL R4GN49
UniProt Splice Variant
Entrez Gene 6273
UniGene Hs.734133
RefSeq NP_005969
HUGO HGNC:10492
OMIM 176993
CCDS CCDS1044
HPRD 01508
IMGT
EMBL BC002829 BC105787 BX470102 M87068 Y07755
GenPept AAH02829 AAI05788 CAA69033 CAI14756