Version 5.4
Homo sapiens Gene: RXFP4
Summary
InnateDB Gene IDBG-103333.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RXFP4
Gene Name relaxin/insulin-like family peptide receptor 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173080
Encoded Proteins
IDBP-103335
relaxin/insulin-like family peptide receptor 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:155941710-155942949
Strand Forward strand
Band q22
Transcripts
ENST00000368318 ENSP00000357301
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004945 angiotensin type II receptor activity
GO:0005515 protein binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0038166 angiotensin-activated signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049741
View Gene Order
ENSBTAG00000046885
Not yet available
Pathways
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_21314
Relaxin receptors pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8TDU9
TrEMBL
UniProt Splice Variant
Entrez Gene 339403
UniGene Hs.449914
RefSeq NM_181885
HUGO HGNC:14666
OMIM 609043
CCDS CCDS1124
HPRD
IMGT
EMBL AB065617 AB083593 AL355388 AY170824 AY288415 AY394502 BC101507 BC101509 EU432129
GenPept AAI01508 AAI01510 AAO17676 AAP72124 AAQ92316 ABY87928 BAB89306 BAC05844 CAH72626
RNA Seq Atlas 339403

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca