Version 5.4
Homo sapiens Gene: SSR2
Summary
InnateDB Gene IDBG-103349.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SSR2
Gene Name signal sequence receptor, beta (translocon-associated protein beta)
Synonyms TLAP; TRAP-BETA; TRAPB
Species Homo sapiens
Ensembl Gene ENSG00000163479
Encoded Proteins
IDBP-103353
signal sequence receptor, beta (translocon-associated protein beta)
IDBP-598558
signal sequence receptor, beta (translocon-associated protein beta)
IDBP-589781
signal sequence receptor, beta (translocon-associated protein beta)
IDBP-597119
signal sequence receptor, beta (translocon-associated protein beta)
IDBP-602620
signal sequence receptor, beta (translocon-associated protein beta)
IDBP-594159
signal sequence receptor, beta (translocon-associated protein beta)
IDBP-599529
signal sequence receptor, beta (translocon-associated protein beta)
IDBP-584703
signal sequence receptor, beta (translocon-associated protein beta)
IDBP-601662
signal sequence receptor, beta (translocon-associated protein beta)
IDBP-591251
signal sequence receptor, beta (translocon-associated protein beta)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:156009048-156020959
Strand Reverse strand
Band q22
Transcripts
ENST00000295702 ENSP00000295702
ENST00000368311
ENST00000472467
ENST00000496742 ENSP00000436201
ENST00000480176
ENST00000484320
ENST00000473699 ENSP00000432831
ENST00000480567 ENSP00000434306
ENST00000472898
ENST00000466905 ENSP00000435692
ENST00000474377 ENSP00000437239
ENST00000488179
ENST00000467041
ENST00000529008 ENSP00000434870
ENST00000532074
ENST00000531790 ENSP00000431366
ENST00000531917 ENSP00000436228
ENST00000526212 ENSP00000434532
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006412 translation
GO:0006613 cotranslational protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041355
View Gene Order
ENSBTAG00000001212
Not yet available
Pathways
NETPATH
REACTOME
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_71
Gene Expression pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_003145
HUGO
OMIM
CCDS CCDS1126
HPRD 02923
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca