Version 5.4
Homo sapiens Gene: TAGLN2
Summary
InnateDB Gene IDBG-103946.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAGLN2
Gene Name transgelin 2
Synonyms HA1756
Species Homo sapiens
Ensembl Gene ENSG00000158710
Encoded Proteins
IDBP-103954
transgelin 2
IDBP-103956
transgelin 2
IDBP-103958
transgelin 2
IDBP-389217
transgelin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The function of this protein has not yet been determined. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:159918107-159925732
Strand Reverse strand
Band q23.2
Transcripts
ENST00000368097 ENSP00000357077
ENST00000368096 ENSP00000357076
ENST00000320307 ENSP00000357075
ENST00000397334 ENSP00000412429
ENST00000478033
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
Experimentally validated
Total 36 [view]
Protein-Protein 33 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0030855 epithelial cell differentiation
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026547
View Gene Order
ENSBTAG00000002068
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
NetPath_24
TSLP pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.517168
RefSeq NM_001277223 NM_001277224 NM_003564
HUGO
OMIM
CCDS CCDS1189 CCDS60314
HPRD 06864
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca