Version 5.4
Mus musculus Gene: Tagln2
Summary
InnateDB Gene IDBG-205555.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tagln2
Gene Name transgelin 2
Synonyms 2700094C18Rik; Sm22a; Sm22B; SM22beta
Species Mus musculus
Ensembl Gene ENSMUSG00000026547
Encoded Proteins
IDBP-258568
transgelin 2
IDBP-258570
transgelin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158710:
The protein encoded by this gene is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The function of this protein has not yet been determined. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:172500047-172507380
Strand Forward strand
Band H3
Transcripts
ENSMUST00000111230 ENSMUSP00000106861
ENSMUST00000111228 ENSMUSP00000106859
ENSMUST00000138296
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0030855 epithelial cell differentiation
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000158710
View Gene Order
ENSBTAG00000002068
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
NetPath_24
TSLP pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9WVA4
TrEMBL
UniProt Splice Variant
Entrez Gene 21346
UniGene Mm.271711
RefSeq NM_178598
OMIM
CCDS CCDS35784
HPRD
IMGT
MGI ID MGI:1312985
MGI Symbol Tagln2
EMBL AF149291 AF465519 AK151576 AK167395 AK167922 AK171088 AK172892 BC009076 BC049861 CH466520
GenPept AAD37787 AAH09076 AAH49861 AAM54133 BAD32170 BAE30516 BAE39484 BAE39928 BAE42241 EDL39010
RNA Seq Atlas 21346

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca