Version 5.4
Homo sapiens Gene: SCYL3
Summary
InnateDB Gene IDBG-104732.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCYL3
Gene Name SCY1-like 3 (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000000457
Encoded Proteins
IDBP-104727
SCY1-like 3 (S. cerevisiae)
IDBP-104734
SCY1-like 3 (S. cerevisiae)
IDBP-104736
SCY1-like 3 (S. cerevisiae)
IDBP-389592
SCY1-like 3 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:169849631-169894267
Strand Reverse strand
Band q24.2
Transcripts
ENST00000367772 ENSP00000356746
ENST00000367771 ENSP00000356745
ENST00000367770 ENSP00000356744
ENST00000423670 ENSP00000407993
ENST00000470238
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0016477 cell migration
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0030027 lamellipodium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026584
View Gene Order
ENSBTAG00000014794
Not yet available
Cross-References
SwissProt Q8IZE3
TrEMBL
UniProt Splice Variant
Entrez Gene 57147
UniGene Hs.435560
RefSeq NM_020423 NM_181093 XM_006711465
HUGO HGNC:19285
OMIM 608192
CCDS CCDS1287 CCDS1286
HPRD 07459
IMGT
EMBL AF540957 AK292507 AL031297 AL117233 AY144493 BC014662 CH471067
GenPept AAH14662 AAN23123 AAN41656 BAF85196 CAB52564 CAB55300 CAI23517 CAI23518 EAW90867
RNA Seq Atlas 57147

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca