Version 5.4
Homo sapiens Gene: QSOX1
Summary
InnateDB Gene IDBG-105161.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol QSOX1
Gene Name quiescin Q6 sulfhydryl oxidase 1
Synonyms Q6; QSCN6
Species Homo sapiens
Ensembl Gene ENSG00000116260
Encoded Proteins
IDBP-105163
quiescin Q6 sulfhydryl oxidase 1
IDBP-105165
quiescin Q6 sulfhydryl oxidase 1
IDBP-246489
quiescin Q6 sulfhydryl oxidase 1
IDBP-389784
quiescin Q6 sulfhydryl oxidase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:180154834-180204030
Strand Forward strand
Band q25.2
Transcripts
ENST00000367602 ENSP00000356574
ENST00000367600 ENSP00000356572
ENST00000392029 ENSP00000375883
ENST00000443059 ENSP00000402170
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0016971 flavin-linked sulfhydryl oxidase activity
GO:0016972 thiol oxidase activity
Biological Process
GO:0006457 protein folding
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005615 extracellular space
GO:0030173 integral component of Golgi membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033684
View Gene Order
ENSBTAG00000014191
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.28456 Hs.518374 Hs.559604 Hs.719176
RefSeq NM_001004128 NM_002826
HUGO
OMIM
CCDS CCDS1337 CCDS30950
HPRD 08043
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca