Homo sapiens Gene: MR1
Summary
InnateDB Gene IDBG-105193.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MR1
Gene Name major histocompatibility complex, class I-related
Synonyms HLALS;
Species Homo sapiens
Ensembl Gene ENSG00000153029
Encoded Proteins
major histocompatibility complex, class I-related
major histocompatibility complex, class I-related
major histocompatibility complex, class I-related
major histocompatibility complex, class I-related
major histocompatibility complex, class I-related
major histocompatibility complex, class I-related
Protein Structure
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:181033425-181061938
Strand Forward strand
Band q25.3
Transcripts
ENST00000367580 ENSP00000356552
ENST00000282990 ENSP00000282990
ENST00000367579 ENSP00000356551
ENST00000367578
ENST00000438435
ENST00000434571 ENSP00000388504
ENST00000486453
ENST00000617803 ENSP00000478976
ENST00000614012 ENSP00000477563
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0032393 MHC class I receptor activity
GO:0042605 peptide antigen binding
Biological Process
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002367 cytokine production involved in immune response
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0006955 immune response
GO:0007165 signal transduction
GO:0019882 antigen processing and presentation
GO:0032611 interleukin-1 beta production
GO:0032620 interleukin-17 production
GO:0045087 innate immune response
GO:0050829 defense response to Gram-negative bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0042612 MHC class I protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q95460
TrEMBL
UniProt Splice Variant
Entrez Gene 3140
UniGene Hs.101840 Hs.13500 Hs.724159
RefSeq NM_001194999 NM_001195000 NM_001195035 NM_001531 XM_005245115
HUGO HGNC:4975
OMIM 600764
CCDS CCDS1342 CCDS53440 CCDS53441 CCDS53442
HPRD 09012
IMGT
EMBL AF010446 AF010447 AF031469 AF039526 AF223407 AH006983 AJ249778 AK222910 AK290374 AK304645 AL356267 BC012485 CH471067 U22963
GenPept AAC50174 AAC72900 AAD01442 AAD01443 AAD01933 AAD02172 AAF40170 AAH12485 BAD96630 BAF83063 BAG65423 CAB77667 CAH72302 CAH72303 CAH72304 CAH72305 EAW91095 EAW91097 EAW91098
ImmGen MR1 (murine)
RNA Seq Atlas 3140