Version 5.4
| Homo sapiens Gene: ARPC5 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-105317.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | ARPC5 | ||||||||||||||||||
| Gene Name | actin related protein 2/3 complex, subunit 5, 16kDa | ||||||||||||||||||
| Synonyms | ARC16; dJ127C7.3; p16-Arc | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000162704 | ||||||||||||||||||
| Encoded Proteins |
actin related protein 2/3 complex, subunit 5, 16kDa
actin related protein 2/3 complex, subunit 5, 16kDa
actin related protein 2/3 complex, subunit 5, 16kDa
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 1:183620846-183635757 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q25.3 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Regulation of actin dynamics for phagocytic cup formation pathway
Developmental Biology pathway
EPHB-mediated forward signaling pathway
Innate Immune System pathway
Axon guidance pathway
Immune System pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
EPH-Ephrin signaling pathway
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| KEGG |
Regulation of actin cytoskeleton pathway
Pathogenic Escherichia coli infection pathway
Fc gamma R-mediated phagocytosis pathway
Bacterial invasion of epithelial cells pathway
Shigellosis pathway
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| INOH | |||||||||||||||||||
| PID NCI |
ErbB1 downstream signaling
RAC1 signaling pathway
CDC42 signaling events
PDGFR-beta signaling pathway
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| Cross-References | |||||||||||||||||||
| SwissProt | O15511 | ||||||||||||||||||
| TrEMBL | B1ALC0 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 10092 | ||||||||||||||||||
| UniGene | |||||||||||||||||||
| RefSeq | NM_001270439 NM_005717 | ||||||||||||||||||
| HUGO | HGNC:708 | ||||||||||||||||||
| OMIM | 604227 | ||||||||||||||||||
| CCDS | CCDS1357 CCDS58050 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AF006088 AF017807 AL137800 BC057237 CH471067 | ||||||||||||||||||
| GenPept | AAB64193 AAB70561 AAH57237 CAC19687 CAI19482 EAW91163 | ||||||||||||||||||
| RNA Seq Atlas | 10092 | ||||||||||||||||||