Version 5.4
Homo sapiens Gene: LMOD1
Summary
InnateDB Gene IDBG-105797.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMOD1
Gene Name leiomodin 1 (smooth muscle)
Synonyms 1D; 64kD; D1; SM-LMOD
Species Homo sapiens
Ensembl Gene ENSG00000163431
Encoded Proteins
IDBP-105799
leiomodin 1 (smooth muscle)
IDBP-810140
leiomodin 1 (smooth muscle)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008]
The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves\' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:201896452-201946588
Strand Reverse strand
Band q32.1
Transcripts
ENST00000367288 ENSP00000356257
ENST00000616739 ENSP00000480209
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005523 tropomyosin binding
Biological Process
GO:0006936 muscle contraction
GO:0051694 pointed-end actin filament capping
Cellular Component
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048096
View Gene Order
ENSBTAG00000021576
Not yet available
Pathways
NETPATH
REACTOME
REACT_20558
Smooth Muscle Contraction pathway
REACT_17044
Muscle contraction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q9BV00
UniProt Splice Variant
Entrez Gene 25802
UniGene
RefSeq NM_012134
HUGO HGNC:6647
OMIM 602715
CCDS CCDS53457
HPRD
IMGT
EMBL BC001755
GenPept AAH01755
RNA Seq Atlas 25802

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca