Version 5.4
Homo sapiens Protein: LMOD1
Summary
InnateDB Protein IDBP-105799.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMOD1
Protein Name leiomodin 1 (smooth muscle)
Synonyms 1D; 64kD; D1; SM-LMOD;
Species Homo sapiens
Ensembl Protein ENSP00000356257
InnateDB Gene IDBG-105797 (LMOD1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000269PubMed:11350761}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:11350761}.
Disease Associations
Tissue Specificity Smooth muscle (heart, skeletal muscle, colon and small intestine), a subset of striated muscle fibers, and at low level in thyroid. {ECO:0000269PubMed:10520227, ECO:0000269PubMed:11350761}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005523 tropomyosin binding
Biological Process
GO:0006936 muscle contraction
GO:0051694 pointed-end actin filament capping
Cellular Component
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003124 WH2 domain
IPR004934 Tropomodulin
PFAM PF02205
PF03250
PRINTS
PIRSF
SMART SM00246
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P29536
PhosphoSite PhosphoSite-P29536
TrEMBL B4DIX9
UniProt Splice Variant
Entrez Gene 25802
UniGene
RefSeq NP_036266
HUGO HGNC:6647
OMIM 602715
CCDS CCDS53457
HPRD 04093
IMGT
EMBL AC099676 AK295824 AL513217 BC080187 X54162
GenPept AAH80187 BAG58641 CAA38101 CAH72278

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca