InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: ELF3

Summary

InnateDB Gene

IDBG-105810.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ELF3

Gene Name

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

Synonyms

EPR-1; ERT; ESE-1; ESX

Species

Homo sapiens

Ensembl Gene

ENSG00000163435

Encoded Proteins

IDBP-105814

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

IDBP-105816

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

IDBP-105818

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

IDBP-389890

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:202007945-202017188

Strand

Forward strand

Band

q32.1

Transcripts

ENST00000359651	ENSP00000352673
ENST00000367284	ENSP00000356253
ENST00000367283	ENSP00000356252
ENST00000446188	ENSP00000405162
ENST00000495848
ENST00000490203
ENST00000498017
ENST00000470384
ENST00000479874
ENST00000475698

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	39 [view]
Protein-Protein	31 [view]
Protein-DNA	6 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0001824	blastocyst development
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0006954	inflammatory response
GO:0007275	multicellular organismal development
GO:0008544	epidermis development
GO:0009653	anatomical structure morphogenesis
GO:0030198	extracellular matrix organization
GO:0030855	epithelial cell differentiation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060056	mammary gland involution

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000003051

View Gene Order

ENSBTAG00000008756

Not yet available

Pathways

NETPATH

NetPath_4

EGFR1 pathway

REACTOME

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.603657 Hs.743671

RefSeq

NM_001114309 NM_004433

HUGO

OMIM

CCDS

CCDS1419

HPRD

03722

IMGT

EMBL

GenPept

RNA Seq Atlas