Version 5.4
Homo sapiens Gene: FAIM3
Summary
InnateDB Gene IDBG-106292.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAIM3
Gene Name Fas apoptotic inhibitory molecule 3
Synonyms FCMR; TOSO
Species Homo sapiens
Ensembl Gene ENSG00000162894
Encoded Proteins
IDBP-106294
Fas apoptotic inhibitory molecule 3
IDBP-389970
Fas apoptotic inhibitory molecule 3
IDBP-584676
Fas apoptotic inhibitory molecule 3
IDBP-598935
Fas apoptotic inhibitory molecule 3
IDBP-585742
Fas apoptotic inhibitory molecule 3
IDBP-600916
Fas apoptotic inhibitory molecule 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:206904386-206923247
Strand Reverse strand
Band q32.1
Transcripts
ENST00000367091 ENSP00000356058
ENST00000442471 ENSP00000404136
ENST00000474041
ENST00000463473 ENSP00000436799
ENST00000528654
ENST00000525793 ENSP00000432936
ENST00000529560 ENSP00000437331
ENST00000533312
ENST00000530505 ENSP00000436316
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002376 immune system process
GO:0006968 cellular defense response
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005576 extracellular region
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042474
View Gene Order
ENSBTAG00000019796
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.58831
RefSeq NM_001142473 NM_005449 XM_005273351
HUGO
OMIM
CCDS CCDS1473 CCDS44304
HPRD 09349
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca