Version 5.4
Homo sapiens Gene: INTS7
Summary
InnateDB Gene IDBG-106526.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INTS7
Gene Name integrator complex subunit 7
Synonyms C1orf73; INT7
Species Homo sapiens
Ensembl Gene ENSG00000143493
Encoded Proteins
IDBP-106530
integrator complex subunit 7
IDBP-106532
integrator complex subunit 7
IDBP-106534
integrator complex subunit 7
IDBP-390006
integrator complex subunit 7
IDBP-811029
integrator complex subunit 7
IDBP-811079
integrator complex subunit 7
IDBP-811077
integrator complex subunit 7
IDBP-811081
integrator complex subunit 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3\'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:211940399-212035542
Strand Reverse strand
Band q32.3
Transcripts
ENST00000366994 ENSP00000355961
ENST00000366993 ENSP00000355960
ENST00000366992 ENSP00000355959
ENST00000440600 ENSP00000388908
ENST00000469606 ENSP00000481687
ENST00000475798 ENSP00000483346
ENST00000461212
ENST00000462910
ENST00000460867
ENST00000612340 ENSP00000481102
ENST00000619805 ENSP00000484371
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 14 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0000077 DNA damage checkpoint
GO:0016180 snRNA processing
GO:0071479 cellular response to ionizing radiation
Cellular Component
GO:0005694 chromosome
GO:0032039 integrator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037461
View Gene Order
ENSBTAG00000018548
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.369285 Hs.629852
RefSeq NM_001199809 NM_001199811 NM_001199812 NM_015434
HUGO
OMIM
CCDS CCDS1501 CCDS55683 CCDS55684 CCDS55685
HPRD 08522
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca