Version 5.4
Mus musculus Gene: Ints7
Summary
InnateDB Gene IDBG-208794.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ints7
Gene Name integrator complex subunit 7
Synonyms 5930412E23Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000037461
Encoded Proteins
IDBP-208798
integrator complex subunit 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143493:
This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3\'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:191575763-191622672
Strand Forward strand
Band H6
Transcripts
ENSMUST00000045450 ENSMUSP00000036277
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0000077 DNA damage checkpoint
GO:0016180 snRNA processing
GO:0071479 cellular response to ionizing radiation
Cellular Component
GO:0005694 chromosome
GO:0032039 integrator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143493
View Gene Order
ENSBTAG00000018548
Not yet available
Cross-References
SwissProt Q7TQK1
TrEMBL
UniProt Splice Variant
Entrez Gene 77065
UniGene Mm.338175 Mm.472270
RefSeq NM_178632 XM_006497213 XM_006497214
OMIM
CCDS CCDS35825
HPRD
IMGT
MGI ID MGI:1924315
MGI Symbol Ints7
EMBL AK085336 AK085362 AK086462 BC054120
GenPept AAH54120 BAC39426 BAC39430 BAC39671
RNA Seq Atlas 77065

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca