Version 5.4
Homo sapiens Gene: RGS7
Summary
InnateDB Gene IDBG-107674.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGS7
Gene Name regulator of G-protein signaling 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000182901
Encoded Proteins
IDBP-107676
regulator of G-protein signaling 7
IDBP-107678
regulator of G-protein signaling 7
IDBP-107680
regulator of G-protein signaling 7
IDBP-107682
regulator of G-protein signaling 7
IDBP-107686
regulator of G-protein signaling 7
IDBP-295752
regulator of G-protein signaling 7
IDBP-390178
regulator of G-protein signaling 7
IDBP-390179
regulator of G-protein signaling 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:240775514-241357230
Strand Reverse strand
Band q43
Transcripts
ENST00000366565 ENSP00000355523
ENST00000366564 ENSP00000355522
ENST00000366563 ENSP00000355521
ENST00000348120 ENSP00000341242
ENST00000366562 ENSP00000355520
ENST00000401882 ENSP00000385508
ENST00000440928 ENSP00000404399
ENST00000446183 ENSP00000390138
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0031681 G-protein beta-subunit binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0035556 intracellular signal transduction
GO:0038032 termination of G-protein coupled receptor signaling pathway
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005834 heterotrimeric G-protein complex
GO:0005886 plasma membrane
GO:0043234 protein complex
GO:0044292 dendrite terminus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026527
View Gene Order
ENSBTAG00000005410
Not yet available
Pathways
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
INOH
INOH website
GPCR signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.595944 Hs.655739
RefSeq NM_001282773 NM_001282775 NM_001282778 NM_002924 XM_005273218 XM_005273221 XM_006711800 XM_006711801
HUGO
OMIM
CCDS CCDS31071 CCDS60457 CCDS60458 CCDS60459
HPRD 03948
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca