Version 5.4
Homo sapiens Gene: OPN3
Summary
InnateDB Gene IDBG-107701.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OPN3
Gene Name opsin 3
Synonyms ECPN; PPP1R116
Species Homo sapiens
Ensembl Gene ENSG00000054277
Encoded Proteins
IDBP-107703
opsin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:241590102-241677376
Strand Reverse strand
Band q43
Transcripts
ENST00000366554 ENSP00000355512
ENST00000462265
ENST00000469376
ENST00000490673
ENST00000463155
ENST00000478849
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0008020 G-protein coupled photoreceptor activity
GO:0009881 photoreceptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007602 phototransduction
GO:0009583 detection of light stimulus
GO:0009584 detection of visible light
GO:0018298 protein-chromophore linkage
GO:0042752 regulation of circadian rhythm
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000026525
View Gene Order
Pathways
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_18426
Opsins pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.743368
RefSeq NM_014322
HUGO
OMIM
CCDS CCDS31072
HPRD 05985
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca