InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: OPN3

Summary

InnateDB Protein

IDBP-107703.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OPN3

Protein Name

opsin 3

Synonyms

ECPN; PPP1R116;

Species

Homo sapiens

Ensembl Protein

ENSP00000355512

InnateDB Gene

IDBG-107701 (OPN3)

Protein Structure

UniProt Annotation

Function

May play a role in encephalic photoreception.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0008020	G-protein coupled photoreceptor activity
GO:0009881	photoreceptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007602	phototransduction
GO:0009583	detection of light stimulus
GO:0009584	detection of visible light
GO:0018298	protein-chromophore linkage
GO:0042752	regulation of circadian rhythm