Version 5.4
Homo sapiens Gene: SDCCAG8
Summary
InnateDB Gene IDBG-107744.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SDCCAG8
Gene Name serologically defined colon cancer antigen 8
Synonyms BBS16; CCCAP; CCCAP SLSN7; hCCCAP; NPHP10; NY-CO-8; SLSN7
Species Homo sapiens
Ensembl Gene ENSG00000054282
Encoded Proteins
IDBP-107746
serologically defined colon cancer antigen 8
IDBP-390203
serologically defined colon cancer antigen 8
IDBP-810167
serologically defined colon cancer antigen 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:243256034-243500092
Strand Forward strand
Band q43
Transcripts
ENST00000366541 ENSP00000355499
ENST00000435549 ENSP00000410200
ENST00000490065
ENST00000491888
ENST00000482234
ENST00000476722 ENSP00000473868
ENST00000496361
ENST00000463012
ENST00000493334
ENST00000463042
ENST00000497459
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0030010 establishment of cell polarity
GO:0035148 tube formation
Cellular Component
GO:0005813 centrosome
GO:0005814 centriole
GO:0005829 cytosol
GO:0005911 cell-cell junction
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026504
View Gene Order
ENSBTAG00000017775
Not yet available
Pathways
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_15364
Loss of Nlp from mitotic centrosomes pathway
REACT_15451
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_115566
Cell Cycle pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_006642 XM_006711727 XM_006724964
HUGO
OMIM
CCDS CCDS31075
HPRD 10215
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca