Version 5.4
Homo sapiens Gene: TFB2M
Summary
InnateDB Gene IDBG-107841.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFB2M
Gene Name transcription factor B2, mitochondrial
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000162851
Encoded Proteins
IDBP-107843
transcription factor B2, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:246540560-246566324
Strand Reverse strand
Band q44
Transcripts
ENST00000366514 ENSP00000355471
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity
GO:0003712 transcription cofactor activity
GO:0008649 rRNA methyltransferase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000154 rRNA modification
GO:0006355 regulation of transcription, DNA-templated
GO:0006390 transcription from mitochondrial promoter
GO:0006391 transcription initiation from mitochondrial promoter
GO:0010467 gene expression
GO:0031167 rRNA methylation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0042645 mitochondrial nucleoid
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_367
Mitochondrial transcription initiation pathway
REACT_200751
Organelle biogenesis and maintenance pathway
REACT_200788
Mitochondrial biogenesis pathway
REACT_1484
Transcription from mitochondrial promoters pathway
REACT_200608
Transcriptional activation of mitochondrial biogenesis pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9H5Q4
TrEMBL A0A024R5R8
UniProt Splice Variant
Entrez Gene 64216
UniGene Hs.7395
RefSeq NM_022366
HUGO HGNC:18559
OMIM 607055
CCDS CCDS1627
HPRD
IMGT
EMBL AF529366 AK026314 AK026835 AL356583 BC003383 CH471148
GenPept AAH03383 AAQ09600 BAB15441 BAB15566 CAI16399 EAW77149 EAW77153
RNA Seq Atlas 64216

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca